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Blood Clots



The acute phase of coronary disease begins when an atherosclerotic plaque ruptures.  

Intravascular structures are exposed and there is release of potent substances into the blood 
which stimulate the coagulation system causing blood to clot. 

This is called thrombus formation.










Image source:
http://medicinembbs.blogspot.com/2011/01/images-for-cad.html









Click below to learn about about how blood clots.












Image source : Clotbuster Archives



Clot formation begins with the platelet, an irregular, disc-shaped particle in the blood that assists in blood clotting.  


The platelet interacts with the ruptured plaque and it components by adhering to the site of injury.

Once attached it becomes activated. The activated platelet releases a variety of substances, which attract other platelets, and causes them to aggregate at the site of the vascular injury.

This leads to the formation of a platelet plug.



















Image Source: Boehringer Ingleheim International











Image Source: Boehringer Ingleheim International




Image Source: Boehringer Ingleheim International







Image Source: Boehringer Ingleheim Internatiional










Image Source: Boehringer Ingleheim International





Clot formation begins with the platelet, an irregular, disc-shaped particle in the blood that assists in blood clotting.  


The platelet interacts with the ruptured plaque and it components by adhering to the site of injury. 

Once attached it becomes activated. The activated platelet releases a variety of substances, which attract other platelets, and causes them to aggregate at the site of the vascular injury. 

This leads to the formation of a platelet plug.